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GlossaryAngiogenesis (neovascularization)

formation of new blood vessels from existing ones

Angiogenesis is the process by which new blood vessels form from pre-existing ones. This is crucial for wound healing, growth, and development, as well as in pathological conditions like cancer, where tumors stimulate angiogenesis to secure a blood supply for their growth.

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research Neovascularization During Healing of Wounds Treated with Dermal Substitutes and Fibrin Glue in Nude Mice

August 2004 in “Journal of the American College of Surgeons”

Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.

research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

76 citations, February 2021 in “International Journal of Molecular Sciences”

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

research Capture of Endothelial Cells Under Flow Using Immobilized Vascular Endothelial Growth Factor

60 citations, February 2015 in “Biomaterials”

A surface with VEGF can specifically capture endothelial cells from flowing fluids.

research Gene Therapy to Enhance Angiogenesis in Chronic Wounds

36 citations, August 2022 in “Molecular Therapy — Nucleic Acids”

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

research Platelet-Rich Plasma for Hair Restoration

16 citations, March 2020 in “Facial Plastic Surgery Clinics of North America”

Platelet-Rich Plasma (PRP), a substance from a patient's own blood, can stimulate hair regrowth in people with Androgenetic Alopecia (AGA) who haven't had success with other treatments, but more research is needed to optimize its use.

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community Clearing the air on how non-surgical treatments really work

18 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.