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    Mitochondria-Targeted Biophysical Priming of Autologous Biologics for Skin Regeneration and Wound Repair

    February 2026 in “ International Journal of Molecular Sciences ”
    Geun-Ho Kang, Kilyong Lee, Chang Hwan Jeon … SungHoon Cho
    Studysummary In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.
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    Research cited in this study 6

    1. Platelet-Rich Plasma: Molecular Mechanisms, Actions, and Clinical Applications in the Human Body International Journal of Molecular Sciences · 2025
    2. Use of Platelet Rich Plasma for Skin Rejuvenation Skin Research and Technology · 2024
    3. Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature International journal of molecular sciences · 2024
    4. Combinatorial Influence of Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma Treatment on Cutaneous Wound Healing in BALB/c Mice Journal of Burn Care & Research · 2023
    5. Mechanical Stretching Can Modify the Papillary Dermis Pattern and Papillary Fibroblast Characteristics During Skin Regeneration Journal of Investigative Dermatology · 2022
    6. Photobiomodulation of Human Dermal Fibroblasts In Vitro: Decisive Role of Cell Culture Conditions and Treatment Protocols on Experimental Outcome Scientific Reports · 2017