Advances in Regenerative Medicine-Based Approaches for Skin Regeneration and Rejuvenation

    February 2025 in “ Frontiers in Bioengineering and Biotechnology ”
    Nathalia Silva Dutra Alves, Gustavo Roncoli Reigado, Mayara Santos … Viviane Abreu Nunes
    Studysummary This review covers advancements in skin repair and rejuvenation technologies, highlighting potential benefits of stem cell therapy, bioengineered skin substitutes, PRP, exosome therapies, and gene editing for conditions such as chronic wounds and genetic disorders, though challenges in accessibility, safety, and long-term effectiveness remain.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 33

    1. Autologous Platelet Concentrates in Aesthetic Medicine Periodontology 2000 · 2024
    2. Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration Cosmetics · 2024
    3. Regenerative Medicine in the Treatment of Specific Dermatologic Disorders: A Systematic Review of Randomized Controlled Clinical Trials Stem cell research & therapy · 2024
    4. Use of Platelet Rich Plasma for Skin Rejuvenation Skin Research and Technology · 2024
    5. The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration Biomedicines · 2024
    6. Hydrogel-Based Skin Regeneration International Journal of Molecular Sciences · 2024
    7. Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Promotes Skin Regeneration and Rejuvenation: From Mechanism to Therapeutics Cell proliferation · 2023
    8. Fat Transplant: Amazing Growth and Regeneration of Cells and Rebirth With the Miracle of Fat Cells Journal of cosmetic dermatology · 2023
    9. Application of Stem Cells in Regenerative Medicine MedComm · 2023
    10. Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing Stem cell research & therapy · 2023
    11. Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine Physiological Research · 2023
    12. Advances and Innovations of 3D Bioprinting Skin Biomolecules · 2022
    13. A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders Journal of Dermatological Treatment · 2022
    14. Regenerative Medicine-Based Treatment for Vitiligo: An Overview Biomedicines · 2022
    15. Biofabrication of Human Skin with Its Appendages Advanced Healthcare Materials · 2022
    16. Stem Cell-Based Tissue Engineering for the Treatment of Burn Wounds: A Systematic Review of Preclinical Studies Stem Cell Reviews and Reports · 2022
    17. Applications of the Regenerative Capacity of Platelets in Modern Medicine Cytokine & growth factor reviews · 2021
    18. 3D Skin Bioprinting: Future Potential for Skin Regeneration Postepy Dermatologii I Alergologii · 2021
    19. Rise of Stem Cell Therapies in Aesthetics Clinics in Dermatology · 2021
    20. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021
    21. The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics Pharmacological research · 2021
    22. Application of Metal-Based Biomaterials in Wound Repair Engineered Regeneration · 2021
    23. Epidermal Growth Factor in Aesthetics and Regenerative Medicine: Systematic Review Journal of Cutaneous and Aesthetic Surgery · 2021
    24. Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis Biomedicines · 2020
    25. Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020 International Journal of Molecular Sciences · 2020
    26. Hopes and Limits of Adipose-Derived Stem Cells and Mesenchymal Stem Cells in Wound Healing International journal of molecular sciences · 2020
    27. Platelet-Rich Plasma Accelerates Skin Wound Healing by Promoting Re-Epithelialization Burns & Trauma · 2020
    28. Functional Skin Grafts: Where Biomaterials Meet Stem Cells Stem Cells International · 2019
    29. Adipose-Derived Cellular and Cell-Derived Regenerative Therapies in Dermatology and Aesthetic Rejuvenation Ageing Research Reviews · 2019
    30. The Use of Platelet-Rich Plasma in Aesthetic and Regenerative Medicine: A Comprehensive Review Aesthetic Plastic Surgery · 2018
    31. Cellular Therapy with Human Autologous Adipose-Derived Adult Cells of Stromal Vascular Fraction for Alopecia Areata Stem Cell Research & Therapy · 2018
    32. Tissue Engineering of Skin and Regenerative Medicine for Wound Care Burns & Trauma · 2018
    33. Next Generation Human Skin Constructs as Advanced Tools for Drug Development Experimental Biology and Medicine · 2017