TLDR Platelet-rich plasma speeds up skin wound healing.
The study concluded that platelet-rich plasma (PRP) significantly accelerated skin wound healing by promoting re-epithelialization, enhancing angiogenesis, and facilitating wound contraction and collagen deposition. Conducted on C57/BL6 mice with 5 subjects per group, the research demonstrated that PRP reduced inflammatory cytokines like IL-17 and IL-1β, increased local vessel intensity, and enhanced the secretion of growth factors such as VEGF and IGF-1. PRP also improved the survival, migration, and proliferation of epidermal stem cells, aiding their differentiation into adult cells. These findings provided a preliminary foundation for the clinical use of PRP in wound healing, although further investigation into the underlying mechanisms was needed.
44 citations
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February 2020 in “Expert Opinion on Biological Therapy” PRP, especially AA-PRP, can help improve hair growth in androgenetic alopecia.
71 citations
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February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
16 citations
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December 2019 in “Journal of Cellular and Molecular Medicine” Sonicated platelet-rich plasma boosts hair growth by activating stem cells.
4 citations
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October 2019 in “Skin appendage disorders” PRP injections safely increase hair density and thickness in androgenetic alopecia.
14 citations
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March 2019 in “Journal of Cosmetic Dermatology” Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.
87 citations
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February 2019 in “Tissue Engineering Part B Reviews” Platelet-rich plasma can effectively treat and prevent tissue infections.
51 citations
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March 2019 in “Journal of cellular physiology” Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
November 2025 in “International Journal of Molecular Sciences” PRP shows promise in healing and regeneration but needs standardized protocols for consistent results.
7 citations
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December 2022 in “Frontiers in Bioengineering and Biotechnology” Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
9 citations
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November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
70 citations
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
August 2023 in “International journal of medical science and clinical research studies” PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
