Reviewing and Exploring the Prospects of Platelet-Rich Plasma Therapy in Pediatric Surgical Wound Management

August 2023 in “ International journal of medical science and clinical research studies ”

Devina Subagio, Ahmad Fawzy

platelet-rich plasma PRP growth factors cytokines cell proliferation tissue regeneration

TLDR PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.

The review explores the potential of Platelet-Rich Plasma (PRP) therapy in pediatric surgical wound management, highlighting its efficacy in accelerating wound healing and reducing scar tissue formation. Clinical studies, including one with 34 pediatric cases showing a 68% success rate, support PRP's benefits in various procedures like cleft lip repair and burn management. PRP's mechanism involves growth factors and cytokines that promote cell proliferation and tissue regeneration. Despite its promise, PRP therapy carries risks such as infection and allergic reactions, necessitating further research to refine protocols and ensure cost-effectiveness in clinical practice.

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