The Clinical Efficacy and Safety of Autologous Activated Platelet-Rich Plasma Injection in Androgenetic Alopecia

January 2020 in “ Skin appendage disorders ”

Niluka Dilrukshi Paththinige, Janaka Akarawita, Geetha Jeganathan

autologous activated platelet-rich plasma androgenetic alopecia hair density hair thickness PRP injections anti-apoptotic regulators peri-follicular vascular plexus PRP androgenic alopecia

TLDR PRP injections safely increase hair density and thickness in androgenetic alopecia.

A study from 3 years ago found that autologous activated platelet-rich plasma injection is a safe and effective treatment for androgenetic alopecia, resulting in increased hair density and thickness. The study involved 20-30 patients who received multiple treatment sessions and showed no major complications. PRP injections promote hair growth by activating anti-apoptotic regulators and increasing the peri-follicular vascular plexus. More studies are needed to confirm its efficacy.

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13 / 13 results

research Caspase-1 Level Is Higher in the Scalp in Androgenetic Alopecia

27 citations , July 2012 in “Dermatologic Surgery”

Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations , July 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

research Promising Therapies for Treating and Preventing Androgenic Alopecia

36 citations , June 2012 in “PubMed”

There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Hair Growth and Rejuvenation: An Overview

81 citations , June 2010 in “Journal of Dermatological Treatment”

The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.

research Male Androgenetic Alopecia

100 citations , May 2010 in “Expert Opinion on Pharmacotherapy”

Hair loss in men treated best with early medication or transplant, new treatments researched.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , November 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

193 citations , December 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

research Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle

149 citations , April 2004 in “Journal of Dermatological Science”

Minoxidil boosts hair growth by increasing cell production and survival.

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

21 citations , January 2002 in “Journal of Cutaneous Medicine and Surgery”

Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

23 citations , January 2002 in “Journal of Cutaneous Medicine and Surgery”

Finasteride helps hair growth by decreasing cell death in hair follicles.

research Finasteride and the Hair Cycle

26 citations , May 2000 in “Journal of The American Academy of Dermatology”

Finasteride improves hair growth.

research Psychological effects of androgenetic alopecia on women: Comparisons with balding men and with female control subjects

222 citations , October 1993 in “Journal of The American Academy of Dermatology”

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

9 / 9 results

research Patient Satisfaction and Clinical Effects of Platelet-Rich Plasma on Pattern Hair Loss in Male and Female Patients

September 2022 in “Cureus”

research Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review

1 citations , August 2021 in “Cosmoderma”

research Systematic Review of Platelet-Rich Plasma in Treating Alopecia: Focusing on Efficacy, Safety, and Therapeutic Durability

24 citations , February 2021 in “Dermatologic Therapy”

Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.

research Evaluation of the Effect of Autologous Platelet-Rich Plasma on Androgenic Alopecia

October 2020 in “Journal of Cosmetic and Laser Therapy”

Using your own platelet-rich plasma (PRP) can effectively treat hair loss, increasing hair density and width with no side effects.

research The Clinical Efficacy and Safety of Autologous Activated Platelet-Rich Plasma Injection in Androgenetic Alopecia

4 citations , January 2020 in “Skin appendage disorders”

PRP injections safely increase hair density and thickness in androgenetic alopecia.

research A Split Head Study of Efficacy of Placebo Versus Platelet-Rich Plasma Injections in the Treatment of Androgenic Alopecia

33 citations , April 2017 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.

The Clinical Efficacy and Safety of Autologous Activated Platelet-Rich Plasma Injection in Androgenetic Alopecia

Cited in this study

research Caspase-1 Level Is Higher in the Scalp in Androgenetic Alopecia

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

research Promising Therapies for Treating and Preventing Androgenic Alopecia

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

research Hair Growth and Rejuvenation: An Overview

research Male Androgenetic Alopecia

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

research Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle

research Finasteride and the Hair Cycle

research Psychological effects of androgenetic alopecia on women: Comparisons with balding men and with female control subjects

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