A Split Head Study of Efficacy of Placebo Versus Platelet-Rich Plasma Injections in the Treatment of Androgenic Alopecia

January 2017 in “ Journal of Cutaneous and Aesthetic Surgery ”

Dilip Kachhawa, Gauri Vats, Durgesh Sonare, P.P. Rao, Sandeep Khuraiya, Rohit Kataiya

platelet-rich plasma androgenic alopecia hair density hair quality male pattern hair loss placebo PRP

TLDR Platelet-rich plasma injections can effectively treat male pattern hair loss, improving hair density and quality with high patient satisfaction.

In 2017, a study was conducted on 50 male patients with androgenic alopecia. They were treated with platelet-rich plasma (PRP) injections on one side of the scalp and a placebo on the other side, every 21 days for a total of six sessions. The results indicated a decrease in hair loss and new hair growth, with digital image analysis showing improved hair density and quality. The study concluded that PRP injections can effectively treat male pattern hair loss with no major side effects and high patient satisfaction. However, it was also suggested that a larger, randomized, double-blind study is needed to confirm these findings.

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Research cited in this study

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Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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