Regenerative Medicine in the Treatment of Specific Dermatologic Disorders: A Systematic Review of Randomized Controlled Clinical Trials

    June 2024 in “ Stem cell research & therapy
    Alireza Jafarzadeh, Arash Pour Mohammad, Haniyeh Keramati, Roya Zeinali, Mina Khosravi, Azadeh Goodarzi
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    TLDR Regenerative medicine shows promise for treating skin disorders like hair loss and vitiligo.
    This systematic review analyzed 64 randomized controlled trials involving 2,888 patients to evaluate the effectiveness of regenerative medicine in treating various dermatologic disorders, particularly androgenetic alopecia (AGA) and vitiligo. The study found high effectiveness rates for regenerative treatments, with PRP being the most frequently used method, showing significant improvements in hair density and count for AGA and repigmentation for vitiligo. Other methods like autologous epidermal melanocyte/keratinocyte cell transplantation also demonstrated significant effectiveness. The review underscores the promising role of regenerative medicine in dermatology but calls for further clinical trials to validate these results.
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