Randomized Control Trial to Study the Efficacy and Safety of Platelet-Rich Plasma as Intraoperative Holding Solution in Hair Restoration Surgery: A Pilot Study

July 2021 in “ Medical journal, Armed Forces India ”

Vikas Pathania, Aradhana Sood, Nagendra Singh Beniwal, Sukriti Baveja, Prerna Shankar, Seema Patrikar

platelet-rich plasma androgenetic alopecia hair restoration surgery shock effluvium follicular unit grafts PRP AGA

TLDR Using platelet-rich plasma in hair restoration surgery significantly improves hair density after 6 months and is safe to use.

This pilot study involved 20 cases of androgenetic alopecia (AGA) and examined the efficacy and safety of platelet-rich plasma (PRP) as an intraoperative holding solution in hair restoration surgery. The results showed that the PRP group had a faster recovery from 'shock effluvium' and a significantly higher hair density at 6 months (P < 0.05). The final hair density in the PRP group was 31.0 (±4.9 SD), compared to 25.5 (±2.5 SD) in the non-PRP group. The study concluded that PRP significantly improves the outcome in hair restoration surgery by improving the mean density of the implanted follicular unit grafts at 6 months and is safe for use in hair restoration surgery.

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