Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia

January 2021 in “ Journal of Cosmetic Dermatology ”

Wafaa S. Ramadan, Arwa M. Hassan, Mayada Ismail, Yasmina Ahmed El Attar

platelet-rich plasma androgenetic alopecia hair density hair thickness intradermal injection PRP AGA

TLDR Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

A study conducted on 126 patients with androgenetic alopecia (AGA) found that adding platelet-rich plasma (PRP) to medical therapy significantly improved hair density and thickness. The study suggests that PRP can be a safe and effective treatment option for AGA with minimal side effects and downtime. The most effective method of administration was found to be intradermal injection. The study recommends using PRP as an additional treatment for AGA.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

12 / 12 results

Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation

research Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation

69 citations, April 2019 in “Biomedicines”

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.

Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil

research Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil

24 citations, January 2019 in “Journal of Cosmetic Dermatology”

Combining platelet-rich plasma, microneedling, and minoxidil improves hair growth.

research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol

45 citations, September 2018 in “International Journal of Women's Dermatology”

PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.

research Trichologic Response of Platelet-Rich Plasma in Androgenetic Alopecia Is Maintained During Combination Therapy

15 citations, March 2018 in “Journal of The American Academy of Dermatology”

PRP therapy improves hair density and thickness in AGA patients, even with other treatments.

research Microneedling for the Treatment of Hair Loss

58 citations, December 2017 in “Journal of The European Academy of Dermatology and Venereology”

Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.

Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

research Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study

19 citations, May 2017 in “Dermatologic Surgery”

Combining platelet-rich plasma with 5% minoxidil solution improves hair regrowth in androgenetic alopecia patients.

research Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia

39 citations, August 2016 in “Journal of Dermatological Treatment”

Stem cell therapy may help treat tough hair loss cases.

research Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia

57 citations, May 2016 in “Journal of Dermatological Treatment”

PRP therapy may effectively treat hair loss, but more research needed.

research Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model

55 citations, January 2016 in “Annals of Dermatology”

Microneedle stimulation can increase hair growth in mice.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations, January 2013 in “International Journal of Trichology”

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations, March 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

research Characteristics of Androgenetic Alopecia in Asian Populations

51 citations, January 2012 in “Annals of Dermatology”

Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.

Related Community Posts Join

6 / 77 results

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 90 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What else is good. Besides the big 3.

in Chat 36 upvotes 1 month ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2675 upvotes 4 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

Related Research

7 / 7 results

research Efficacy of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor on the Treatment of Androgenic Alopecia

December 2022 in “Plastic and Reconstructive Surgery”

PRPF is a safer and more effective treatment for hair loss than PRP.

research Effect of Platelet-Rich Plasma (PRP) on Hairfall (Khalitya) Along with Ayurvedic Medicines: A Case Study

August 2021 in “Journal of emerging technologies and innovative research”

PRP combined with Ayurvedic medicine may effectively treat hair loss.

research Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia

5 citations, January 2021 in “Journal of Cosmetic Dermatology”

Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.

research Platelet-Rich Plasma for Hair Loss

12 citations, January 2021 in “Springer eBooks”

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations, January 2015 in “International Journal of Trichology”

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

research Experience Using Platelet-Rich Plasma in the Treatment of Androgenic Alopecia

April 2014 in “The FASEB Journal”

Platelet-rich plasma therapy can reduce hair loss and enhance hair growth in androgenetic alopecia patients, with no side effects observed.

research Disorders of Hair

July 2013 in “DeckerMed Medicine”

The document's conclusion cannot be provided because the document is not readable or understandable.