Efficacy of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor on the Treatment of Androgenic Alopecia

    December 2022 in “ Plastic and Reconstructive Surgery ”
    Qian Qu, Ye He, Zhi Guo … Yong Miao
    Studysummary In this study, PRPF treatment was more effective than PRP alone in improving hair count and hair quality in androgenetic alopecia patients, with PRPF showing significant improvements in various hair growth parameters and having no statistical differences observed in the placebo group.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.lww.com →
    Discuss this study in the Community →

    Research cited in this study 24

    1. Systematic Review: The Potential Implications of Different Platelet-Rich Plasma Concentrations in Regenerative Medicine for Tissue Repair International Journal of Molecular Sciences · 2020
    2. A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia Expert Opinion on Biological Therapy · 2020
    3. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    4. Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia Expert Opinion on Biological Therapy · 2020
    5. Impact of Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma and Activated Platelet-Rich Plasma in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation International Journal of Molecular Sciences · 2020
    6. Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia BioMed Research International · 2020
    7. Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia International Journal of Molecular Sciences · 2019
    8. Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades Clinical Drug Investigation · 2019
    9. Platelet-Rich Plasma for Treating Androgenic Alopecia: A Systematic Review Aesthetic Plastic Surgery · 2019
    10. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    11. Platelet-Rich Plasma and Micrografts Enriched with Autologous Human Follicle Mesenchymal Stem Cells Improve Hair Regrowth in Androgenetic Alopecia: Biomolecular Pathway Analysis and Clinical Evaluation Biomedicines · 2019
    12. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    13. Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss Stem cell investigation · 2017
    14. Platelet-Rich Plasma in Combination With 5% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study Dermatologic Surgery · 2017
    15. Evaluation of Non-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017
    16. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    17. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
    18. The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation BioMed Research International · 2014
    19. Guidelines for Management of Androgenetic Alopecia Based on BASP Classification: The Asian Consensus Committee Guideline Journal of The European Academy of Dermatology and Venereology · 2012
    20. Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012
    21. Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study Annals of Dermatology · 2012
    22. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    23. In Vivo Promoted Growth of Mice Hair Follicles by the Controlled Release of Growth Factors Biomaterials · 2003
    24. Epidermal Growth Factor And Fibroblast Growth Factor Accelerate Proliferation Of Human Hair Bulb Papilla Cells And Root Sheath Fibroblasts Cultured In Vitro British Journal of Dermatology · 1987

    Related research 10

    1. Effectiveness of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia: A Prospective Cohort Study from Guntur, Andhra Pradesh Journal of Evidence Based Medicine and Healthcare · 2021
    2. Autologous Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia: Results of a 54-Patient Prospective Study Skinmed · 2021
    3. Concentrated Growth Factor from Autologous Platelet Promotes Hair Growth in Androgenetic Alopecia Journal of Biomedical Science and Engineering · 2019
    4. Dermoscopic Pre- And Post-Treatment Evaluation In Patients With Androgenetic Alopecia On Platelet-Rich Plasma—A Prospective Study Journal of Cosmetic Dermatology · 2018
    5. Platelet-Rich Plasma on Female Androgenetic Alopecia: Tested on 10 Patients Journal of Cosmetic Dermatology · 2018
    6. Injections of Platelet-Rich Plasma for Androgenic Alopecia: A Systematic Review Journal of Stomatology, Oral and Maxillofacial Surgery · 2017
    7. Original Articles: The Application of Platelet-Rich Plasma in the Treatment of Androgenic Alopecia 2015
    8. Efficacy of Platelet-Rich Plasma in Treatment of Androgenic Alopecia Asian Journal of Transfusion Science · 2015
    9. Australian Trial of Topical Minoxidil and Placebo in Early Male Pattern Baldness Australasian Journal of Dermatology · 1990
    10. 2% Topical Minoxidil Solution in Male-Pattern Baldness: Preliminary European Results Dermatology · 1987