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    Evaluation of Platelet-Rich Plasma Plus Basic Fibroblast Growth Factor Combined With Minoxidil in the Treatment of Androgenetic Alopecia: A Randomized Controlled Trial

    Shulian Wu, Shizhao Liu, Jian Chen … Qian Qu
    Studysummary This prospective randomized controlled trial found that combining platelet-rich plasma plus basic fibroblast growth factor injections with topical minoxidil significantly improves hair count and growth rate in androgenetic alopecia patients compared to either treatment alone.
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    Research cited in this study 20

    1. Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways Frontiers in Medicine · 2022
    2. Clinical Observation of Basic Fibroblast Growth Factor (bFGF) Combined with Minoxidil in the Treatment of Male Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    3. Combination Therapy with Platelet-Rich Plasma and Minoxidil Leads to Better Clinical Results Than Monotherapy in Men with Androgenetic Alopecia International Journal of Trichology · 2022
    4. Safety and Efficacy of ALRV5XR in Men with Androgenetic Alopecia: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial EClinicalMedicine · 2021
    5. Platelet-Rich Plasma for Androgenic Alopecia: A Randomized, Placebo-Controlled, Double-Blind Study and Combined Mice Model Experiment Journal of Cosmetic Dermatology · 2021
    6. Platelet-Rich Plasma Has a Place in the Treatment of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2020
    7. Comparative Evaluation of the Clinical Efficacy of PRP Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia International Journal of Molecular Sciences · 2020
    8. Autologous Activated Platelet-Rich Plasma in Hair Growth: A Pilot Study in Male Androgenetic Alopecia with In Vitro Bioactivity Investigation Journal of Cosmetic Dermatology · 2020
    9. Heterogeneity in Amount of Growth Factors Secreted by Platelets in Platelet-Rich Plasma Samples from Alopecia Patients Experimental dermatology · 2020
    10. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    11. Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study Experimental Dermatology · 2020
    12. Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study Journal of Cosmetic Dermatology · 2019
    13. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    14. FGF Family: From Drug Development to Clinical Application International Journal of Molecular Sciences · 2018
    15. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    16. Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss Wound Repair and Regeneration · 2014
    17. Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012
    18. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    19. Sulfation of Minoxidil by Human Platelet Sulfotransferase Clinica Chimica Acta · 1987
    20. Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography Journal of Investigative Dermatology · 1984

    Related research 10

    1. Effectiveness of Multimodality Therapy Using Minoxidil and Microneedling for the Treatment of Alopecia: A Systematic Review and Meta-Analysis 2023
    2. Pediatric Androgenetic Alopecia: An Updated Review Journal der Deutschen Dermatologischen Gesellschaft · 2023
    3. A Survey of Patient Attitudes Towards Topical Minoxidil in the Treatment of Hair Loss PubMed · 2022
    4. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    5. Topical Minoxidil Adherence in Alopecia Patients Journal of Investigative Dermatology · 2019
    6. The Use of Trichoscopy to Assess the Efficacy of Topical Minoxidil 2% Solution in Patients with Female Pattern Hair Loss Zagazig university medical journal · 2019
    7. What’s New in Hair Loss Dermatologic Clinics · 2019
    8. The Efficacy of Topical Minoxidil for Non-Scarring Alopecia: A Systematic Review PubMed · 2019
    9. A Review of the Use of Platelet-Rich Plasma for the Treatment of Androgenic Alopecia Journal of Investigative Dermatology · 2018
    10. Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment Skin appendage disorders · 2015