Autologous Activated Platelet-Rich Plasma in Hair Growth: A Pilot Study in Male Androgenetic Alopecia with In Vitro Bioactivity Investigation

April 2021 in “ Journal of Cosmetic Dermatology ”

Yinghui Zhou, Qing-Mei Liu, Yanshuang Bai, Kai Yang, Yaqi Ye, Ke-Jia Wu, Huang Junhong, Yue Zhang, Xuewenjun Zhang, Traidit Thianthanyakij, Ji'an Wang, Yifei Zhu, Jun Lin, Wenyu Wu

platelet-rich plasma androgenetic alopecia growth factors cytokines cell proliferation angiogenesis vascular remodeling PRP

TLDR PRP treatment significantly increased hair density and thickness in male hair loss.

A pilot study with male participants found that autologous activated platelet-rich plasma (PRP) treatment resulted in a significant increase in hair density and thickness in androgenetic alopecia. PRP contains growth factors and cytokines that promote cell proliferation, angiogenesis, and vascular remodeling. However, further research is needed to determine the role of PRP in treating alopecia. The study suggests that PRP may be a promising treatment for hair loss.

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8 / 8 results

research Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

53 citations , January 2018 in “Skin appendage disorders”

PRP treatment helps hair growth in most cases, but more research needed.

research Injections of Platelet-Rich Plasma for Androgenic Alopecia: A Systematic Review

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PRP injections help regrow hair, reduce hair loss, and increase hair thickness, but effects decrease without ongoing treatment.

research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling

43 citations , January 2016 in “Cellular physiology and biochemistry”

Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.

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58 citations , January 2015 in “International Journal of Trichology”

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205 citations , August 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Androgens and Hair Loss: An In-Depth Analysis of Androgenetic Alopecia

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The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

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Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

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203 citations , February 2005 in “Journal of The American Academy of Dermatology”

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

9 / 9 results

research Autologous Activated Platelet-Rich Plasma in Hair Growth: A Pilot Study in Male Androgenetic Alopecia with In Vitro Bioactivity Investigation

4 citations , April 2021 in “Journal of Cosmetic Dermatology”

PRP treatment significantly increased hair density and thickness in male hair loss.

research Concentrated Growth Factor from Autologous Platelet Promotes Hair Growth in Androgenetic Alopecia

1 citations , March 2019 in “Journal of Biomedical Science and Engineering”

research Platelet-Rich Plasma—An 'Elixir' for Treatment of Alopecia: Personal Experience on 117 Patients with Review of Literature

31 citations , July 2017 in “Stem cell investigation”

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research Androgens and Hair Growth

209 citations , September 2008 in “Dermatologic Therapy”

Androgens can both increase and decrease hair growth in different parts of the body.

research Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles

57 citations , November 1998 in “Wound Repair and Regeneration”

Hair papilla cells can create and regenerate hair bulbs under the right conditions.