Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

May 2020 in “ Journal of Cosmetic Dermatology ”

Özlem Dicle, Asli Bilgic, Kemal Hakan Gülkesen

platelet-rich plasma androgenetic alopecia hair density PRP treatment male AGA PRP AGA

TLDR PRP injections improve hair density in male hair loss.

This document is a summary of five different studies that evaluated the effectiveness and safety of platelet-rich plasma (PRP) injections in treating male androgenetic alopecia (AGA). The studies involved a total of 130 male patients with AGA who received PRP or a placebo. The results showed that PRP treatment had positive effects on AGA in males, with a significant increase in hair density observed after treatment. However, further studies are needed to identify factors that may affect PRP treatment performance, such as the stage of the disease. Overall, PRP injections can be a safe and effective treatment option for male AGA.

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21 / 21 results

research Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades

19 citations , September 2019 in “Clinical Drug Investigation”

Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.

research The Effect of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia

12 citations , March 2019 in “Journal of Cosmetic Dermatology”

PRP injections improve hair thickness and density in hair loss, but more research needed.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations , December 2018 in “Journal of The European Academy of Dermatology and Venereology”

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

research Automated Digital Image Analysis (TrichoScan) in Male Patients with Androgenetic Alopecia: Comparison with Manual Marking of Hairs on Trichoscopic Images

5 citations , January 2018 in “Skin Research and Technology”

TrichoScan needs optimization as it underestimated hair density by 38.9% compared to manual counting.

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

61 citations , October 2016 in “Journal of Cosmetic and Laser Therapy”

Platelet-rich plasma (PRP) was found not effective in treating male-patterned hair loss.

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation

183 citations , January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , November 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

research Minoxidil: Mechanisms of Action on Hair Growth

397 citations , February 2004 in “British Journal of Dermatology”

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

Hair follicle biology advancements may lead to better hair growth disorder treatments.

research Prevalence of Male Pattern Hair Loss in 18–49 Year Old Men

50 citations , December 1998 in “Dermatologic Surgery”

Hair loss is more common in men aged 18-49 and increases with age.

1 / 1 results

research Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

9 citations , May 2020 in “Journal of Cosmetic Dermatology”

PRP injections improve hair density in male hair loss.

Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

Cited in this study

research Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades

research The Effect of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

research Automated Digital Image Analysis (TrichoScan) in Male Patients with Androgenetic Alopecia: Comparison with Manual Marking of Hairs on Trichoscopic Images

research Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

research Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis

research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

research A Study of the Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia in Males

research Platelet-Rich Plasma for Treatment of Non-Scarring Hair Loss: Systematic Review of Literature

research Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss