Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

September 2019 in “ Journal of Cosmetic Dermatology ”

Özlem Dicle, Asli Bilgic, Kemal Hakan Gülkesen

platelet-rich plasma androgenetic alopecia hair density PRP treatment male AGA PRP AGA

TLDR PRP injections improve hair density in male hair loss.

This document is a summary of five different studies that evaluated the effectiveness and safety of platelet-rich plasma (PRP) injections in treating male androgenetic alopecia (AGA). The studies involved a total of 130 male patients with AGA who received PRP or a placebo. The results showed that PRP treatment had positive effects on AGA in males, with a significant increase in hair density observed after treatment. However, further studies are needed to identify factors that may affect PRP treatment performance, such as the stage of the disease. Overall, PRP injections can be a safe and effective treatment option for male AGA.

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Research cited in this study

21 / 21 results

research Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades

19 citations, June 2019 in “Clinical Drug Investigation”

Platelet-rich plasma injections significantly improve hair density and thickness in both male and female pattern hair loss, especially in early stages.

research The Effect of Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia

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PRP injections improve hair thickness and density in hair loss, but more research needed.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations, May 2018 in “Journal of The European Academy of Dermatology and Venereology”

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Automated Digital Image Analysis (TrichoScan) in Male Patients with Androgenetic Alopecia: Comparison with Manual Marking of Hairs on Trichoscopic Images

research Automated Digital Image Analysis (TrichoScan) in Male Patients with Androgenetic Alopecia: Comparison with Manual Marking of Hairs on Trichoscopic Images

5 citations, January 2018 in “Skin Research and Technology”

TrichoScan needs optimization as it underestimated hair density by 38.9% compared to manual counting.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version

145 citations, November 2017 in “Journal of The European Academy of Dermatology and Venereology”

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research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

348 citations, July 2017 in “Skin appendage disorders”

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

research Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

53 citations, June 2017 in “Skin appendage disorders”

PRP treatment helps hair growth in most cases, but more research needed.

research Platelet-Rich Plasma for Androgenetic Alopecia: Does It Work? Evidence from Meta-Analysis

64 citations, March 2017 in “Journal of Cosmetic Dermatology”

PRP treatment may increase hair density and reduce hair loss, but more research is needed.

research Platelet-Rich Plasma for Treatment of Non-Scarring Hair Loss: Systematic Review of Literature

25 citations, March 2017 in “Journal of Dermatological Treatment”

Platelet-rich plasma treatment for non-scarring hair loss shows mixed results and needs more research.

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20 citations, September 2016 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma treatment significantly increased hair diameter and density, stopped hair fall, and boosted hair growth in men with hair loss, with no reported side effects.

research Efficacy of Platelet-Rich Plasma in the Treatment of Androgenetic (Male-Patterned) Alopecia: A Pilot Randomized Controlled Trial

61 citations, September 2016 in “Journal of Cosmetic and Laser Therapy”

Platelet-rich plasma (PRP) was found not effective in treating male-patterned hair loss.

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57 citations, May 2016 in “Journal of Dermatological Treatment”

PRP therapy may effectively treat hair loss, but more research needed.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations, April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Therapeutic Efficacy of Autologous Platelet-Rich Plasma and Polydeoxyribonucleotide on Female Pattern Hair Loss

54 citations, December 2014 in “Wound Repair and Regeneration”

PRP injections may improve hair thickness and density in female hair loss patients.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

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183 citations, January 2014 in “BioMed Research International”

AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.

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251 citations, October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

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397 citations, February 2004 in “British Journal of Dermatology”

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

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1113 citations, August 1999 in “The New England Journal of Medicine”

Hair follicle biology advancements may lead to better hair growth disorder treatments.

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50 citations, December 1998 in “Dermatologic Surgery”

Hair loss is more common in men aged 18-49 and increases with age.

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Related Research

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research Platelet-Rich Plasma Injections in the Treatment of Male Androgenetic Alopecia: A Randomized Placebo-Controlled Crossover Study

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PRP injections improve hair density in male hair loss.