Autologous Concentrated Growth Factors Combined With Topical Minoxidil for the Treatment of Male Androgenetic Alopecia: A Randomized Controlled Clinical Trial

    Poh-Ching Tan, Pei-Qi Zhang, Yun Xie … Kai Liu
    Studysummary This study found that combining concentrated growth factor injections with minoxidil treatment significantly improved hair growth and participant satisfaction in male patients with androgenetic alopecia compared to minoxidil alone.
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    Research cited in this study 27

    1. Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae Growth Hormone & IGF Research · 2024
    2. Concentrated Growth Factor from Autologous Platelet Promotes Hair Growth in Androgenetic Alopecia Journal of Biomedical Science and Engineering · 2019
    3. Systematic Review of Platelet-Rich Plasma (PRP) Preparation and Composition for the Treatment of Androgenetic Alopecia Journal of Cosmetic Dermatology · 2018
    4. Evaluating Platelet-Rich Plasma Therapy for Facial Aesthetics and Alopecia Plastic and Reconstructive Surgery · 2018
    5. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    6. Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase International Journal of Molecular Sciences · 2017
    7. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    8. Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology Journal of Cosmetic Dermatology · 2015
    9. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    10. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    11. The Endocrinology of Baldness Hormones · 2014
    12. Exogenous IGF-1 Promotes Hair Growth by Stimulating Cell Proliferation and Downregulating TGF-β1 in C57BL/6 Mice In Vivo Growth Hormone & IGF Research · 2014
    13. The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study Journal of The European Academy of Dermatology and Venereology · 2012
    14. Guidelines for Management of Androgenetic Alopecia Based on BASP Classification: The Asian Consensus Committee Guideline Journal of The European Academy of Dermatology and Venereology · 2012
    15. Minoxidil Use in Dermatology, Side Effects, and Recent Patents Recent Patents on Inflammation & Allergy Drug Discovery · 2012
    16. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    17. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
    18. Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities British Journal of Dermatology · 2010
    19. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    20. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    21. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    22. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    23. Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment Journal of The American Academy of Dermatology · 2002
    24. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    25. The Induction by Topical Minoxidil of Increased Fenestration in the Perifollicular Capillary Wall British Journal of Dermatology · 1999
    26. The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats Journal of Dermatology · 1990
    27. Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia Clinics in Dermatology · 1988

    Related research 7

    1. Concomitant Androgenetic Alopecia and Alopecia Areata Successfully Treated with a Combination of Topical Corticosteroids and Minoxidil Solution: A Case Report Journal of Pigmentary Disorders · 2017
    2. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    3. Male Androgenetic Alopecia Treated with Microneedling Alone or Associated with Injectable Minoxidil by Microinfusion of Drugs into the Skin Surgical and Cosmetic Dermatology · 2016
    4. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    5. Sensitization to Saw Palmetto and Minoxidil in Separate Topical Extemporaneous Treatments for Androgenetic Alopecia Australasian Journal of Dermatology · 2002
    6. Topical Minoxidil in the Treatment of Alopecia Areata Plastic & Reconstructive Surgery · 1985
    7. Topical Minoxidil in the Treatment of Alopecia Areata BMJ · 1983