The Effect of Conditioned Media From Human Adipocyte-Derived Mesenchymal Stem Cells on Androgenetic Alopecia After Nonablative Fractional Laser Treatment

August 2020 in “ Dermatologic Surgery ”

Young-In Lee, Ji-Young Kim, Je-Min Kim, Hyojin Park, Ju Lee

conditioned media human adipocyte-derived mesenchymal stem cells ADSC-CM androgenetic alopecia nonablative fractional laser treatment hair density hair volume stem cell therapy laser treatment

Studysummary In this study, human ADSC-CM treatment following nonablative fractional laser significantly increased hair density and volume in patients with androgenetic alopecia without any reported adverse effects. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the effects of conditioned media from human adipocyte-derived mesenchymal stem cells (ADSC-CM) on androgenetic alopecia (AGA) following nonablative fractional laser treatment. Thirty patients participated, receiving either ADSC-CM or a placebo. Results showed that the ADSC-CM group experienced significantly higher hair density and global improvement scores compared to the placebo group. No adverse effects were reported, suggesting that ADSC-CM application post-laser treatment effectively enhanced hair density and volume in AGA patients.

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