Novel In Vitro Culture Condition Improves the Stemness of Human Dermal Stem/Progenitor Cells

    November 2013 in “ Molecules and Cells ”
    Ji Sung Shim, Tae Ryong Lee, Dong Wook Shin
    Studysummary This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.
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    Research cited in this study 9

    1. Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity Stem Cells and Development · 2013
    2. Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures PLoS ONE · 2012
    3. Enrichment and Characterization of Human Dermal Stem/Progenitor Cells Using Collagen Type IV Journal of Dermatological Science · 2012
    4. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences Between Sox2-Positive and Sox2-Negative Cells In Vitro and In Vivo Journal of Investigative Dermatology · 2011
    5. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    6. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    7. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    8. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005
    9. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005