Low Molecular Weight Collagen Peptide Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway

    September 2023 in “ Journal of microbiology and biotechnology ”
    Yu Jin Kim, Jung Ok Lee, Jung Min Lee … Beom Joon Kim
    Studysummary This study found that low molecular weight collagen peptide from fish may promote hair growth in both human cells and mice by activating the Wnt/β-catenin signaling pathway.
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    Research cited in this study 28

    1. Keratin-Mediated Hair Growth and Its Underlying Biological Mechanism Communications biology · 2022
    2. Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia Journal of Investigative Dermatology · 2022
    3. TGF-β2 and Collagen Play Pivotal Roles in the Spheroid Formation and Anti-Aging of Human Dermal Papilla Cells Aging · 2021
    4. Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in In Vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures Frontiers in cell and developmental biology · 2021
    5. Getting Under the Skin of Hair Aging: The Impact of the Hair Follicle Environment Experimental Dermatology · 2020
    6. Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods Skin Pharmacology and Physiology · 2020
    7. Induction of Hair Keratins Expression by an Annurca Apple-Based Nutraceutical Formulation in Human Follicular Cells Nutrients · 2019
    8. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    9. Overexpression of Alkaline Phosphatase Improves the Hair-Inductive Capacity of Cultured Human Dermal Papilla Spheres Journal of Dermatological Science · 2019
    10. Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia International Journal of Molecular Sciences · 2019
    11. Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration PubMed · 2019
    12. Generation of Trichogenic Adipose-Derived Stem Cells by Expression of Three Factors Journal of Dermatological Science · 2018
    13. Minoxidil Promotes Hair Growth Through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018
    14. Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2017
    15. Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review PubMed · 2016
    16. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    17. 5α-Reductase Inhibition and Hair Growth Promotion of Some Thai Plants Traditionally Used for Hair Treatment Journal of Ethnopharmacology · 2011
    18. Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin Development · 2011
    19. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    20. Persistent Hair Growth During Treatment With the EGFR Inhibitor Erlotinib Dermatology Online Journal · 2009
    21. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    22. Minoxidil: An Underused Vasodilator for Resistant or Severe Hypertension Journal of Clinical Hypertension · 2004
    23. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    24. Differences in Hair Follicle Dermal Papilla Volume Are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses Journal of Investigative Dermatology · 1999
    25. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    26. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    27. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996
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