Therapeutic Potential of Stem Cells in Follicle Regeneration

    August 2018 in “ Stem Cells International ”
    Agnieszka Owczarczyk-Saczonek, Magdalena Krajewska-Włodarczyk, Anna Kruszewska, Łukasz Banasiak, Waldemar Placek, Wojciech Maksymowicz, Joanna Wojtkiewicz
    Image of study
    TLDR Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
    The 2018 document "Therapeutic Potential of Stem Cells in Follicle Regeneration" explored the use of stem cells, particularly those derived from adipose tissue and Wharton's jelly, in hair follicle regeneration and the treatment of hair loss conditions such as alopecia. The research highlighted the role of various genes, proteins, and signaling pathways in hair growth and follicle development. It also discussed the potential of stem cells in reversing pathological mechanisms contributing to hair loss, regenerating complete hair follicles, and creating new hair follicles from stem cell cultures. However, the document emphasized the need for further research to fully understand the mechanisms involved and to optimize treatment protocols. The document also reviewed several studies that demonstrated the effectiveness of stem cells in promoting hair growth and treating hair loss conditions.
    Discuss this study in the Community →

    Research cited in this study

    59 / 59 results

    Related Community Posts Join

    6 / 328 results

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 6 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

    Related Research

    2 / 2 results