Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche

    April 2016 in “ Cell Transplantation ”
    Inhwa Hwang, Kyung Ah Choi, Hang-Soo Park, Hyesun Jeong, Jeong Ok Kim, Ki Cheon Seol, Han Jin Kwon, In Hyun Park, Sunghoi Hong
    Image of study
    TLDR Neural stem cell extract can safely promote hair growth in mice.
    In a 2016 study, researchers found that neural stem cell (NSC) extract significantly promoted hair growth in mice by activating hair follicle stem cells and dermal papilla cells, and by modulating key signaling pathways such as TGF-β and BMP. The NSC extract increased hair shaft length, growth rate, and hair weight, and it did not cause DNA damage or cell death, indicating its safety for skin treatment. Histological analysis showed an increase in hair follicles and proliferative cells in the hair matrix. The study, which involved in vitro and in vivo experiments with a sample size of n=5 mice per group, suggests that NSC extract could be a potential therapeutic agent for hair loss conditions. The research was funded by various institutions and the authors declared no conflicts of interest.
    Discuss this study in the Community →

    Research cited in this study

    22 / 22 results

    Related Community Posts Join

    6 / 62 results

      community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

      in Progress Pictures  130 upvotes 10 months ago
      The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

      community How much dht does Nizoral shampoo block?

      in Ketoconazole  101 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.

      community I enjoy taking finasteride every day

      in Finasteride/Dutasteride  241 upvotes 6 months ago
      Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

      community Is it possible to transplant all of my hair to one spot on my head?

      in Satire  34 upvotes 5 months ago
      A user humorously discusses wanting to transplant all their hair into one dense circle on their scalp, leaving the rest of their head bald. Replies include a joke about performing the procedure and a story about someone using their hair to fight crime.

      community Anyone excited for CosmeRNA coming this month?

      in Product  171 upvotes 1 year ago
      CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

    Related Research

    7 / 7 results