Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche

    April 2016 in “ Cell Transplantation ”
    Inhwa Hwang, Kyung Ah Choi, Hang-Soo Park … Sunghoi Hong
    Studysummary This study found that neural stem cell extract enhanced hair growth in mice and cells by stimulating hair follicle niches and activating signaling pathways like TGF-β and BMP.
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    Research cited in this study 24

    1. Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin PLOS ONE · 2015
    2. Potential Synergistic Effects of Human Placental Extract and Minoxidil on Hair Growth-Promoting Activity in C57BL/6J Mice Clinical and Experimental Dermatology · 2015
    3. Emerging Interactions Between Skin Stem Cells and Their Niches Nature Medicine · 2014
    4. Treatment of MSCs with Wnt1a-Conditioned Medium Activates DP Cells and Promotes Hair Follicle Regrowth Scientific Reports · 2014
    5. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    6. Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth Proceedings of the National Academy of Sciences of the United States of America · 2013
    7. Valproic Acid Promotes Human Hair Growth in In Vitro Culture Model Journal of Dermatological Science · 2013
    8. The Harmonies Played by TGF-β in Stem Cell Biology Cell Stem Cell · 2012
    9. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012
    10. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
    11. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    12. Establishment and Characterization of an Immortalized Human Dermal Papilla Cell Line BMB Reports · 2011
    13. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    14. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
    15. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    16. Hair Growth Promoting Effects of Adipose Tissue-Derived Stem Cells Journal of Dermatological Science · 2009
    17. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    18. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    19. Hair Follicle Regeneration Using Grafted Rodent and Human Cells Journal of Investigative Dermatology · 2007
    20. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    21. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    22. Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003
    23. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    24. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001

    Related research 8

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    2. Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal npj Regenerative Medicine · 2017
    3. Hair Growth-Promoting Effect of Geranium Sibiricum Extract in Human Dermal Papilla Cells and C57BL/6 Mice BMC Complementary and Alternative Medicine · 2017
    4. Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche Cell Transplantation · 2016
    5. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD71 Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015
    6. Correlation Between Hair Physiology and Hair Loss 2005
    7. The Hair Growth Promoting Effect of Asiasari Radix Extract and Its Molecular Regulation Journal of Dermatological Science · 2005
    8. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996