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Glossary Genes

segments of DNA that encode instructions for protein synthesis

Genes are segments of DNA that act as instructions for building and maintaining the body's cells and tissues. They determine inherited traits, such as eye color or susceptibility to certain diseases, by encoding for specific proteins that perform various functions in the body.

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Research

5 / 1000+ results

research Genes for intermediate filament proteins and the draft sequence of the human genome

287 citations , July 2001 in “Journal of Cell Science”

This study mapped 65 intermediate filament genes in the human genome, highlighting that the majority of keratin-related sequences are inactive pseudogenes, notably for keratins 8 and 18.

research The role of keratin proteins and their genes in the growth, structure and properties of hair

228 citations , January 1997 in “Birkhäuser Basel eBooks”

This article integrates existing literature on hair follicle structure and formation at the cellular and molecular level, reporting no new findings.

research Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

226 citations , August 2006 in “Molecular and Cellular Biology”

This study found that EGFR signaling modulates GLI target gene expression, potentially influencing outer root sheath cell specification and hair growth, and may have implications for cancer.

research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter

215 citations , November 2000 in “Journal of Investigative Dermatology”

This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.

research Keratin gene mutations in disorders of human skin and its appendages

185 citations , December 2010 in “Archives of Biochemistry and Biophysics”

Keratin gene mutations cause various skin and hair disorders, but new research offers hope for future treatments.

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Community Join

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community How far are we from gene editing stem cells and implanting them?

in Research/Science 14 upvotes 6 months ago

Gene editing for hair loss is not yet viable due to technological and economic challenges. Current treatments like Minoxidil, finasteride, and hair transplants remain the most practical options.

community Genetics are so weird and unpredictable

in Minoxidil 118 upvotes 1 year ago

The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.

community Generic Minoxidil 2.5mg and Dutasteride 0.5mg tablet response

4 upvotes 1 month ago

The conversation discusses using Lonitab 2.5mg and Duman 0.5mg for hair loss and considering switching to Dava India's minoxidil and dutasteride tablets. Users suggest sticking with reputable brands like Cipla and Dr. Reddy's, and mention that Dava is trustworthy.

community Does someone knows if GeneTherica is legit for RU58841?

8 upvotes 7 months ago

GeneTherica is discussed as a source for RU58841, with ordering possible via WhatsApp. The conversation focuses on the legitimacy of this supplier for hair loss treatment.

community Gents, heres a 2-year comparison of Fin only treatment. Starting Oral Min this month. Is their some progression? Should I make a switch to Dut?

in Progress Pictures 47 upvotes 8 months ago

The user has been using finasteride for two years to stabilize hair loss and is considering adding oral minoxidil for volume. They are also contemplating switching to dutasteride and possibly getting a hair transplant for better results.

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Learn

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learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

Is the hair transplant procedure performed under local or general anesthesia? Hair transplant procedures are typically performed under local anesthesia.
What is the success rate of hair transplants in Turkey? Turkish clinics advertise success rates of 85% to 99%, but those are self-reported marketing figures: 'success rate' has no agreed clinical definition and no independent data set backs the numbers.
How long does recovery take after a hair transplant? Recovery after a hair transplant typically takes 7 to 14 days for initial healing.

learn Vitamin B1

Thinning hair over time? It might not just be genetics: lack of B1 and B2 could be silently working against you. There is no verified human trial showing that B1 or B2 deficiency causes thinning hair or that correcting it regrows hair; a 2019 review concludes the role of micronutrients in hair loss is real but unclear and still needs controlled trials.

learn Scalp Micropigmentation

How long does scalp micropigmentation take to heal? Scalp micropigmentation typically takes 7-14 days to heal fully.

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

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Clinics

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All 68 clinic results →

Experts

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22
Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi