Fibroproliferative Genes Are Preferentially Expressed in Central Centrifugal Cicatricial Alopecia

    June 2018 in “ Journal of The American Academy of Dermatology ”
    Crystal Aguh, Yemisi Dina, C. Conover Talbot, Luis A. Garza
    Studysummary This study identified upregulation of genes linked to fibroproliferative disorders, such as platelet-derived growth factor and collagen genes, in patients with central centrifugal cicatricial alopecia, suggesting potential therapeutic targets.
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    Research cited in this study 9

    1. Primary Cicatricial Alopecia Journal of The American Academy of Dermatology · 2016
    2. Non-Edg Family LPA Receptors: The Cutting Edge of LPA Research Journal of Biochemistry/˜The œjournal of biochemistry · 2011
    3. Normal Fur Development and Sebum Production Depend on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands Journal of biological chemistry/˜The œJournal of biological chemistry · 2011
    4. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011
    5. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    6. Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist Archives of dermatology · 2009
    7. Central Centrifugal Cicatricial Alopecia: Past, Present, and Future Journal of The American Academy of Dermatology · 2009
    8. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    9. Prostaglandin Metabolism in Human Hair Follicle Experimental Dermatology · 2007