Human Mesenchymal Stem Cell-Derived Conditioned Media for Hair Regeneration Applications

The review from 7 years ago discussed the potential of stem cell therapy for hair regrowth, specifically focusing on the use of conditioned media derived from stem cells. The authors noted that traditional treatments for hair loss, such as drugs (Finasteride and Minoxidil), follicular hair transplant, laser therapy, and serum therapy, have disadvantages and side effects. They suggested that stem cell therapy could be a promising alternative due to its advantages and promising outcomes. The excess of Dihydrotestosterone (DHT) was identified as a major cause of hair loss, as it results in the shrinkage of hair follicles, adversely affecting hair growth. The authors emphasized the unique properties of stem cells and the favorable growth factors they secrete, suggesting strategies to enhance the production of these factors for hair loss therapeutics.