Platelet-Rich Plasma for the Management of Hair Loss: Better Alone or in Combination?

This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.

This study reported that using human follicle stem cells isolated from hair bulge areas increased hair density by about 29% over baseline in patients with androgenetic alopecia, with significant improvements observed 23 weeks after the last treatment.

This study found that 5% activated platelet-rich plasma significantly improved cell proliferation and hair-inductive ability of dermal papilla cells in vitro, and promoted hair follicle formation in mice.

This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.

This review discusses the use of platelet-rich plasma for pattern hair loss treatment and examines existing clinical studies without presenting new clinical results.

This analysis suggests that platelet-rich plasma therapy may be promising for treating androgenetic alopecia, but further controlled trials with standardized measures are needed to confirm its efficacy.

This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.

This case study reports that combining platelet-rich plasma with intradermal triamcinolone acetonide improved hair regrowth and fiber diameter in one patient with alopecia areata compared to triamcinolone alone.

This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.

This study observed that autologous PRP and PDRN injections improved hair thickness and density in women with pattern hair loss, with combined therapy showing greater improvement in thickness than PDRN alone.

In this study using a mouse model, the researchers found that platelet-rich plasma significantly increased the number of newly formed hair follicles and decreased the time for hair formation compared to no treatment.

In this study, platelet-rich plasma significantly increased hair regrowth and reduced symptoms of alopecia areata compared to triamcinolone acetonide or placebo, with no observed side effects.

This study found that PRP combined with dalteparin and protamine microparticles may enhance hair growth by increasing hair thickness compared to PRP alone.

In this study, platelet plasma growth factors from patients' autologous plasma improved follicular unit yield in baldness surgery by 15.1% compared to control areas.

This study suggests that stress negatively affects hair growth by inducing inflammation and early hair cycle transitions in mice, which might inform strategies for managing stress-related hair loss in humans.