TLDR A special stem cell fluid can speed up wound healing and hair growth in mice.
Six years ago, a study investigated the effects of a conditioned medium of umbilical cord mesenchymal stem cells (UC-MSCs) overexpressing Wnt7a on wound healing and hair follicle regeneration in mice. The researchers found that this medium significantly enhanced wound closure rates, with rates of 25.3%, 51.6%, and 91.5% on post-injury days 3, 7, and 14 respectively. It also increased the expression of extracellular matrix molecules in the wound area, accelerated the migration of human dermal fibroblasts into the wound area, and promoted the regeneration of more hair follicles compared to control groups. However, it also inhibited the migratory ability of keratinocytes. The study concluded that this medium can enhance wound repair and hair follicle regeneration in mice.
23 citations,
June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
84 citations,
June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
300 citations,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
72 citations,
April 2008 in “Organogenesis” Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
829 citations,
May 2007 in “Nature” Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
