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GlossaryExtracellular Matrix (ECM)

complex network of proteins and molecules supporting cell structure

The Extracellular Matrix (ECM) is a complex network of proteins and other molecules that surround and support cells within tissues and organs. It provides structural support, influences cell behavior, and plays a crucial role in processes like wound healing and tissue regeneration.

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research ECM1 Modified HF-MSCs Targeting HSC Attenuate Liver Cirrhosis by Inhibiting the TGF-β/Smad Signaling Pathway

18 citations, February 2022 in “Cell Death Discovery”

ECM1-modified stem cells can effectively treat liver cirrhosis.

research Modulation of Macrophage Functions by ECM-Inspired Wound Dressings – A Promising Therapeutic Approach for Chronic Wounds

9 citations, August 2021 in “Biological Chemistry”

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling

5 citations, February 2022 in “Seminars in cell & developmental biology”

Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.

research The Role of Versican in the Skin Extracellular Matrix and Its Interaction with Hyaluronic Acid

2 citations, January 2019 in “Biomecánica”

Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.

High-Throughput Screening of 3D Co-Culture Hair Follicle Mimetic Tissue with Enhanced ECM for the Screening of Hair Growth Promoting Compounds

research High-Throughput Screening of 3D Co-Culture Hair Follicle Mimetic Tissue with Enhanced ECM for the Screening of Hair Growth Promoting Compounds

January 2024 in “Biomaterials Research”

The new 3D system helps test hair growth treatments effectively.

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community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 1 month ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.