Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment

    Mathieu Blais, Rémi Parenteau-Bareil, Sébastien Cadau, François Berthod
    Studysummary This review discusses strategies for regenerating cutaneous nerve function in burn patients and highlights the potential role of autologous skin-derived adult stem cells in improving sensory recovery, but reports no new experimental findings.
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    Research cited in this study 14

    1. Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation Scientific Reports · 2012
    2. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    3. Single Follicular Unit Transplantation Reconstructs Arrector Pili Muscle and Nerve Connections and Restores Functional Hair Follicle Piloerection The Journal of Dermatology · 2012
    4. Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation Pigment Cell & Melanoma Research · 2011
    5. Hair Follicles Guide Nerve Migration In Vitro and In Vivo in Tissue-Engineered Skin Journal of Investigative Dermatology · 2011
    6. De Novo Formation and Ultra-Structural Characterization of a Fiber-Producing Human Hair Follicle Equivalent In Vitro Journal of biotechnology · 2011
    7. Tissue-Engineered Skin Preserving the Potential of Epithelial Cells to Differentiate into Hair After Grafting Tissue Engineering Part A · 2010
    8. SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells Cell stem cell · 2009
    9. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    10. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    11. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005
    12. Developmental Timing of Hair Follicle and Dorsal Skin Innervation in Mice Journal of comparative neurology · 2002
    13. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    14. Characterization of a New Tissue-Engineered Human Skin Equivalent with Hair In Vitro Cellular & Developmental Biology - Animal · 1999