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GlossaryLaminin

protein crucial for cell adhesion and tissue structure

Laminin is a protein found in the extracellular matrix, which is the network of molecules outside cells that provides structural and biochemical support to surrounding cells. It plays a crucial role in tissue architecture, cell adhesion, differentiation, and migration. Laminin is essential for the integrity and function of tissues, including the skin and hair follicles, making it significant in studies related to hair growth and alopecia.

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research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis

102 citations, August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

13 citations, June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia

13 citations, April 2010 in “Journal of dermatological science”

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs

12 citations, May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

Laminin 332 is essential for normal skin cell behavior and structure.

research Spatial And Temporal Control Of Laminin-511 And -332 Expressions During Catagen

6 citations, April 2010 in “Journal of Dermatological Science”

Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.

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