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GlossaryLaminin

protein crucial for cell adhesion and tissue structure

Laminin is a protein found in the extracellular matrix, which is the network of molecules outside cells that provides structural and biochemical support to surrounding cells. It plays a crucial role in tissue architecture, cell adhesion, differentiation, and migration. Laminin is essential for the integrity and function of tissues, including the skin and hair follicles, making it significant in studies related to hair growth and alopecia.

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research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis

102 citations , August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Laminin α5 in the Keratinocyte Basement Membrane Is Required for Epidermal–Dermal Intercommunication

57 citations , May 2016 in “Matrix Biology”

research Deletion of the Epidermis Derived Laminin γ1 Chain Leads to Defects in the Regulation of Late Hair Morphogenesis

19 citations , May 2016 in “Matrix Biology”

Deleting a specific protein in skin cells disrupts normal hair growth and development.

research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

13 citations , June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia

13 citations , April 2010 in “Journal of dermatological science”

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

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community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 4 months ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.