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GlossaryLaminin

protein crucial for cell adhesion and tissue structure

Laminin is a protein found in the extracellular matrix, which is the network of molecules outside cells that provides structural and biochemical support to surrounding cells. It plays a crucial role in tissue architecture, cell adhesion, differentiation, and migration. Laminin is essential for the integrity and function of tissues, including the skin and hair follicles, making it significant in studies related to hair growth and alopecia.

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research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis

102 citations , August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Laminin α5 in the Keratinocyte Basement Membrane Is Required for Epidermal–Dermal Intercommunication

57 citations , May 2016 in “Matrix Biology”

Laminin α5 is essential for skin communication and health.

research Changes in Fibronectin, Laminin, and Type IV Collagen Distribution Relate to Basement Membrane Restructuring During the Rat Vibrissa Follicle Hair Growth Cycle

45 citations , August 1992 in “PubMed”

The rat vibrissa follicle can quickly remodel its basement membrane during hair growth, affecting cell signaling and activity.

research Deletion of the Epidermis Derived Laminin γ1 Chain Leads to Defects in the Regulation of Late Hair Morphogenesis

19 citations , May 2016 in “Matrix Biology”

Deleting a specific protein in skin cells disrupts normal hair growth and development.

research Dual Role of Laminin-511 in Regulating Melanocyte Migration and Differentiation

17 citations , September 2018 in “Matrix Biology”

Laminin-511 is essential for proper melanocyte movement and development in mice.

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community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 5 months ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.