Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions

    September 2021 in “ International Journal of Nanomedicine
    Li Yu, Qing Xiao, Jie Tang, Li Li
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    TLDR Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
    The document "Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions" discusses the potential of extracellular vesicles (EVs) in treating various skin conditions and promoting hair growth. EVs, tiny particles released by cells, play a crucial role in cell-to-cell communication and can carry bioactive molecules. They can be engineered to deliver specific therapeutic agents to targeted cells. EVs have shown potential in treating dermatological conditions, inflammatory skin disorders, and have been used to construct a multi-antigenic nanovaccine against drug-resistant S.aureus. They also enhance wound healing and have shown promise in treating alopecia. EVs sourced from different cells can promote hair growth by enhancing cell proliferation, migration, and differentiation. However, further research is needed to fully understand the potential of EVs and to overcome challenges related to their isolation, characterization, and large-scale production.
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