Platelet-Rich Plasma in Dermatology and Aesthetic Medicine

August 2024 in “ Quality in Sport ”

Łukasz Ochyra, Anna Łopuszyńska

platelet-rich plasma PRP growth factors skin rejuvenation anti-aging hair reconstruction wound healing scar reconstruction pigmentation disorders laser therapy microneedling

TLDR PRP helps with skin, hair, and wound treatments but needs more research for standard use.

Platelet-rich plasma (PRP) is an autologous concentrate of platelets in a small volume of plasma, showing positive effects in aesthetic and regenerative medicine, as well as in dermatological diseases. The review highlights PRP's comprehensive action due to numerous growth factors, demonstrating benefits in skin rejuvenation, anti-aging, hair reconstruction, wound healing, scar reconstruction, and pigmentation disorders. Combining PRP with other treatments like laser therapy or microneedling enhances results. However, further multi-center studies are necessary to standardize treatment protocols and tailor them to specific issues.

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Research cited in this study

14 / 14 results

research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration

1 citations, December 2023 in “Life”

PRP helps skin heal, possibly through special cells called telocytes.

research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action

3 citations, December 2023 in “Biomedicines”

PRP therapy helps skin heal and improve by promoting cell growth and repair.

research A Comprehensive Review on Platelet-Rich Plasma Activation: A Key Player in Accelerating Skin Wound Healing

2 citations, November 2023 in “Curēus”

Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.

research Cellular Senescence: Ageing and Androgenetic Alopecia

January 2023 in “Dermatology”

Ageing and increased senescent cells significantly contribute to common hair loss.

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

1 citations, November 2022 in “Journal of Dermatological Treatment”

Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.

research Platelet Rich Plasma and Its Use in Hair Regrowth: A Review

18 citations, March 2022 in “Drug design, development and therapy”

Platelet-rich plasma (PRP) may help with various hair loss types, but more research is needed to find the best use method.

research Platelet-Rich Plasma in the Treatment of Alopecia Areata: A Review

15 citations, October 2020 in “Journal of Investigative Dermatology Symposium Proceedings”

Platelet-Rich Plasma (PRP) could potentially help regrow hair in people with Alopecia Areata, but more research is needed to confirm its effectiveness.

research Progress in the Use of Platelet-Rich Plasma in Aesthetic and Medical Dermatology

3 citations, August 2020 in “PubMed”

Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.

research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss

86 citations, July 2020 in “International Journal of Molecular Sciences”

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy

65 citations, April 2020 in “International Journal of Molecular Sciences”

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

research Platelet-Rich Plasma: The Journey So Far

18 citations, January 2020 in “Indian Dermatology Online Journal”

Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.

research Platelet-Rich Plasma: Current Applications in Dermatology

25 citations, September 2019 in “PubMed”

Platelet-Rich Plasma (PRP) is helpful for skin and hair treatments and works better when combined with other procedures.

research The Use of Platelet-Rich Plasma in Aesthetic and Regenerative Medicine: A Comprehensive Review

76 citations, December 2018 in “Aesthetic Plastic Surgery”

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

348 citations, July 2017 in “Skin appendage disorders”

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

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Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

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Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

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in Research 830 upvotes 7 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Poor diet and lifestyle contribute to male pattern baldness. Treatments like Minoxidil, dietary changes, and lifestyle adjustments may help slow hair loss.

community How can I get fin in Canada (GP and Derm turned me down) + questions on minoxidil and PRP

6 upvotes 7 years ago

Treatments for hair loss with a focus on finasteride, minoxidil, and platelet-rich plasma (PRP). The user discussed their family history of balding, asked questions about the effectiveness of different treatments, and was discouraged from taking finasteride by medical professionals.

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Research cited in this study

research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration

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