Platelet-Rich Plasma: The Journey So Far

January 2020 in “ Indian Dermatology Online Journal ”

Akanksha Kaushik, Muthu Sendhil Kumaran

platelet-rich plasma PRP alopecia androgenetic alopecia skin rejuvenation cutaneous ulcers acne scar management

TLDR Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.

The 2020 document "Platelet-rich plasma: The journey so far !" reviewed the use of platelet-rich plasma (PRP) in dermatology. PRP, a concentration of platelets in plasma, was used for conditions like alopecia, skin rejuvenation, healing of refractory cutaneous ulcers, and acne scar management. The strongest evidence for PRP's efficacy was in treating androgenetic alopecia and facial skin rejuvenation. However, the routine use of PRP was limited due to a lack of high-quality evidence and large randomized studies. The document also noted that PRP composition and preparation methods were not standardized, and treatment regimens varied widely. The document concluded that while PRP showed promise in various dermatological applications, more extensive and standardized studies were needed to establish its efficacy and safety.

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Research cited in this study

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research Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

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Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.

research Evaluating Platelet-Rich Plasma Therapy for Facial Aesthetics and Alopecia

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PRP therapy may improve skin and hair conditions, but more research with standard methods is needed.

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348 citations, July 2017 in “Skin appendage disorders”

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations, April 2016 in “Dermatologic Surgery”

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Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

39 citations, January 2016 in “Journal of Cutaneous and Aesthetic Surgery”

Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.

research Applications of Platelet-Rich Plasma in Dermatology: A Critical Appraisal of the Literature

79 citations, October 2015 in “Journal of Dermatological Treatment”

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

research Platelet-Rich Plasma in Dermatology: Boon or Bane?

119 citations, January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations, December 2012 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations, September 2011 in “Dermatologic Surgery”

Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations, October 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

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