Platelet-Rich Plasma: The Journey So Far

January 2020 in “ Indian Dermatology Online Journal ”

Akanksha Kaushik, Muthu Sendhil Kumaran

platelet-rich plasma PRP alopecia androgenetic alopecia skin rejuvenation cutaneous ulcers acne scar management

TLDR Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.

The 2020 document "Platelet-rich plasma: The journey so far !" reviewed the use of platelet-rich plasma (PRP) in dermatology. PRP, a concentration of platelets in plasma, was used for conditions like alopecia, skin rejuvenation, healing of refractory cutaneous ulcers, and acne scar management. The strongest evidence for PRP's efficacy was in treating androgenetic alopecia and facial skin rejuvenation. However, the routine use of PRP was limited due to a lack of high-quality evidence and large randomized studies. The document also noted that PRP composition and preparation methods were not standardized, and treatment regimens varied widely. The document concluded that while PRP showed promise in various dermatological applications, more extensive and standardized studies were needed to establish its efficacy and safety.

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19 / 19 results

research Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil

24 citations , October 2019 in “Journal of Cosmetic Dermatology”

Combining platelet-rich plasma, microneedling, and minoxidil improves hair growth.

research Dermoscopic Pre- And Post-Treatment Evaluation In Patients With Androgenetic Alopecia On Platelet-Rich Plasma—A Prospective Study

5 citations , October 2019 in “Journal of Cosmetic Dermatology”

PRP treatment improves hair count, density, and reduces hair loss in AGA patients.

research Efficacy of Platelet-Rich Plasma in Androgenetic Alopecia Patients

14 citations , August 2019 in “Journal of Cosmetic Dermatology”

PRP therapy safely improves hair growth in people with hair loss.

research Platelet-Rich Plasma in Androgenetic Alopecia: A Systematic Review

11 citations , May 2019 in “Dermatologic Therapy”

Not enough evidence to support using platelet rich plasma for hair loss treatment.

research Treatment of Male Pattern Alopecia with Platelet-Rich Plasma: A Double-Blind Controlled Study with Analysis of Platelet Number and Growth Factor Levels

57 citations , March 2019 in “Journal of The American Academy of Dermatology”

Platelet-rich plasma treatment can significantly increase hair count and density in men with pattern baldness, and these improvements can last up to 3 months.

research A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia

18 citations , March 2019 in “International Journal of Trichology”

research The Efficacy of Platelet-Rich Plasma in Hair Restoration and Facial Aesthetics: A Systematic Review and Meta-Analysis

31 citations , January 2019 in “Journal of Cutaneous Medicine and Surgery”

Platelet-Rich Plasma (PRP) therapy can promote hair growth and improve facial aesthetics, including reducing acne scars and facial burns, and it works best with three initial monthly injections.

research Effect of Platelet-Rich Plasma Injection for Rejuvenation of Photoaged Facial Skin

51 citations , December 2018 in “JAMA Dermatology”

PRP injections may improve skin texture and wrinkles based on patient feedback, despite no significant changes seen by dermatologists.

research Problems and Solutions for Platelet-Rich Plasma in Facial Rejuvenation: A Systematic Review

20 citations , October 2018 in “Aesthetic Plastic Surgery”

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

research Evaluating Platelet-Rich Plasma Therapy for Facial Aesthetics and Alopecia

31 citations , May 2018 in “Plastic and Reconstructive Surgery”

PRP therapy may improve skin and hair conditions, but more research with standard methods is needed.

research Platelet-Rich Plasma Versus Tretinoin in Treatment of Striae Distensae: A Comparative Study

22 citations , May 2018 in “Dermatologic Surgery”

Platelet-rich plasma injections are more effective and satisfying for treating skin scars than tretinoin cream.

research A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

348 citations , July 2017 in “Skin appendage disorders”

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

research Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia

136 citations , April 2016 in “Dermatologic Surgery”

PRP treatment helps hair growth and density in androgenetic alopecia patients.

research Outcome of Intra-Operative Injected Platelet-Rich Plasma Therapy During Follicular Unit Extraction Hair Transplant: A Prospective Randomized Study in Forty Patients

39 citations , January 2016 in “Journal of Cutaneous and Aesthetic Surgery”

Injecting platelet-rich plasma during hair transplant surgery improves hair regrowth rate, speeds up skin recovery, and enhances hair quality.

research Applications of Platelet-Rich Plasma in Dermatology: A Critical Appraisal of the Literature

79 citations , October 2015 in “Journal of Dermatological Treatment”

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

research Platelet-Rich Plasma in Dermatology: Boon or Bane?

119 citations , January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

research The Effect of CD34+ Cell-Containing Autologous Platelet-Rich Plasma Injection on Pattern Hair Loss: A Preliminary Study

88 citations , January 2014 in “Journal of The European Academy of Dermatology and Venereology”

Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.

research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth

166 citations , December 2011 in “Dermatologic Surgery”

Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.

research The Role of Platelet Plasma Growth Factors in Male Pattern Baldness Surgery

251 citations , November 2006 in “Plastic and reconstructive surgery/PSEF CD journals”

Using platelet plasma growth factors in baldness surgery can increase the number of hair follicles.

1 / 1 results

research Comparison of the Efficacy of Homologous and Autologous Platelet-Rich Plasma for Treating Androgenic Alopecia

24 citations , February 2018 in “Aesthetic Plastic Surgery”

All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.