Platelet-Rich Plasma Versus Tretinoin in Treatment of Striae Distensae: A Comparative Study

    December 2017 in “ Dermatologic Surgery ”
    Hend Gamil, Samia Ibrahim, Howyda Mohamed Ebrahim, Waleed Albalat
    Image of study
    TLDR Platelet-rich plasma injections are more effective and satisfying for treating skin scars than tretinoin cream.
    The study conducted by Gamil, Hend D. MD; Ibrahim, Samia A. MD; Ebrahim, Howyda M. MD; Albalat, Waleed MD in 2018 compared the effectiveness of platelet-rich plasma (PRP) injections and topical tretinoin 0.05% in treating Striae Distensae (SD), a type of dermal scar. The study involved 30 patients (27 females and 3 males) with bilateral SD. Each patient had half of their selected striae treated with PRP injections and the other half with topical tretinoin. The results showed a statistically significant improvement in SD treated with both PRP and topical tretinoin cream, but the improvement was more significant in the SD treated with PRP injections (p = .015). Patient satisfaction also indicated a greater improvement on the PRP-treated side (p = .003). Both treatments were found to be safe and increased collagen and elastic fibers in the dermis, but PRP was more effective and provided a better therapeutic response than tretinoin.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 79 results

      community What else is good. Besides the big 3.

      in Chat  34 upvotes 2 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community Today doctor scolded me so hard💀

      in Chat  39 upvotes 4 months ago
      A 20-year-old has been using finasteride for 2 years and switched from 5% to 10% minoxidil, causing issues. The doctor now prescribes 5% minoxidil twice daily, dutasteride on alternate days, and 3 PRP sessions for hair regrowth.

      community Finasteride user thinking of going on Minoxidil: custom version vs. generic?

      in Minoxidil  8 upvotes 1 year ago
      A man in his 50s, who has been on Finasteride for 15 years, is considering adding a custom topical Minoxidil blend to his treatment due to recent hairline recession. He questions whether the custom blend is more effective than generic Minoxidil, expresses concerns about shedding and body hair growth, and seeks advice on application timing with styling products and whether to pursue other treatments like PRP or laser.

      community MY Hair Loss Treatment Summary

      in Treatment  11 upvotes 6 months ago
      The conversation is about various hair loss treatments, including finasteride, minoxidil, RU58841, and natural supplements like saw palmetto and pumpkin seed oil. It also covers methods to improve blood circulation, nourish hair follicles, and address underlying health issues like vitamin D deficiency and high cortisol levels.

      community Long-Term Dutasteride Frustration

      in Progress Pictures  22 upvotes 5 months ago
      A user is frustrated with long-term hair loss despite using Dutasteride and Ketoconazole shampoo. Suggestions include trying oral Minoxidil, micro-needling, and a homemade caffeinated rosemary tonic.

    Related Research

    2 / 2 results