TLDR 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
The document reviews recent advancements in 3D bioprinting for skin regeneration, emphasizing innovations in bioink materials and bioprinting techniques that enable the creation of complex, vascularized skin constructs. Key developments include the use of natural hydrogels, synthetic polymers, and decellularized extracellular matrices to enhance printability and mechanical properties. The review highlights the potential of bioprinted skin models for applications in wound healing, disease modeling, and regenerative medicine, with promising results in hair follicle development and vascularization. Despite these advancements, challenges such as achieving long-term stability and clinical viability remain, necessitating further research to overcome these hurdles and realize the full potential of 3D bioprinted skin in medical applications.
18 citations
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July 2022 in “Chemistry - an Asian journal” Scientists created a 3D printed skin that includes hair and layers similar to real skin using a special gel.
70 citations
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February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
44 citations
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February 2020 in “Expert Opinion on Biological Therapy” PRP, especially AA-PRP, can help improve hair growth in androgenetic alopecia.
184 citations
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December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
21 citations
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December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
37 citations
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May 2016 in “Scientific Reports” Combining skin cells with fat-derived stem cells can improve hair growth.
294 citations
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January 2016 in “Stem Cells International” Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
30 citations
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February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
Stem cell therapy shows promise for better burn healing but needs more research and standardization.
24 citations
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August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.