Advances and Innovations of 3D Bioprinting Skin

    December 2022 in “ Biomolecules
    Moon Sung Kang, Jinju Jang, Hyo Jung Jo, Won‐Hyeon Kim, Bongju Kim, Heoung‐Jae Chun, Dohyung Lim, Dong‐Wook Han
    TLDR 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
    The document reviews recent advancements in 3D bioprinting for skin regeneration, emphasizing innovations in bioink materials and bioprinting techniques that enable the creation of complex, vascularized skin constructs. Key developments include the use of natural hydrogels, synthetic polymers, and decellularized extracellular matrices to enhance printability and mechanical properties. The review highlights the potential of bioprinted skin models for applications in wound healing, disease modeling, and regenerative medicine, with promising results in hair follicle development and vascularization. Despite these advancements, challenges such as achieving long-term stability and clinical viability remain, necessitating further research to overcome these hurdles and realize the full potential of 3D bioprinted skin in medical applications.
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