Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications

    January 2016 in “ Stem Cells International
    Ru Dai, Zongjie Wang, Roya Samanipour, Kyo-in Koo, Keekyoung Kim
    TLDR Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
    The document reviewed adipose-derived stem cells (ASCs) as a promising source for tissue engineering and regenerative medicine due to their self-renewal and multipotential differentiation capabilities. ASCs were highlighted as more accessible and easier to harvest compared to bone marrow-derived stem cells. The use of 3D tissue engineering scaffolds was emphasized for better mimicking the in vivo cellular environment, enhancing ASC localization, attachment, proliferation, and differentiation. The paper discussed various biomaterials and methods for ASC proliferation and differentiation in 3D environments, and explored clinical applications, underscoring the potential and feasibility of using tissue-engineered ASCs for tissue and organ transplantation.
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