TLDR Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
The document reviewed adipose-derived stem cells (ASCs) as a promising source for tissue engineering and regenerative medicine due to their self-renewal and multipotential differentiation capabilities. ASCs were highlighted as more accessible and easier to harvest compared to bone marrow-derived stem cells. The use of 3D tissue engineering scaffolds was emphasized for better mimicking the in vivo cellular environment, enhancing ASC localization, attachment, proliferation, and differentiation. The paper discussed various biomaterials and methods for ASC proliferation and differentiation in 3D environments, and explored clinical applications, underscoring the potential and feasibility of using tissue-engineered ASCs for tissue and organ transplantation.
41 citations
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July 2012 in “Stem Cells and Development” Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
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August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
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July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
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April 2022 in “Bioengineering” Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
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March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
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November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.