Stem Cell Therapy for Burns: The Story So Far

August 2021 in “ Biologics ”

Najath Abdul Kareem, Ayesha Aijaz, Marc G. Jeschke

mesenchymal stem cells bone marrow adipose tissue umbilical cord wound healing scarring skin regeneration growth factors inflammation angiogenesis MSCs

TLDR Stem cell therapy shows promise in improving burn wound healing.

The document "Stem Cell Therapy for Burns: Story so Far" reviews the progress and potential of stem cell therapy in treating burn injuries, highlighting the promise of mesenchymal stem cells (MSCs) from various sources like bone marrow, adipose tissue, and umbilical cord in enhancing wound healing, reducing scarring, and improving skin regeneration. Key mechanisms include the secretion of growth factors, modulation of inflammation, and enhancement of angiogenesis. While preclinical and clinical trials show positive outcomes, challenges such as immune rejection, ethical concerns, and the need for standardized protocols remain. Further research is needed to optimize these therapies and confirm their long-term benefits.

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Research cited in this study

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research Efficacy of Stem Cell Therapy for Burn Wounds: A Systematic Review and Meta-Analysis of Preclinical Studies

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