Effects of Hair Follicle Stem Cells on Partial-Thickness Burn Wound Healing and Tensile Strength

December 2019 in “ Iranian Biomedical Journal ”

Azar Babakhani, Malihe Nobakht, Hamidreza Pazoki‐Toroudi, Mostafa Dahmardehei, Paria Hashemi, Javad Mohajer Ansari, Parisa Ramhormozi, Abazar Yari, Fatemeh Heidari

hair follicle stem cells partial-thickness burn wounds tensile strength wound healing burn injuries

Studysummary This study found that hair follicle stem cells could enhance burn wound healing and improve tissue tensile strength in rats.

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research Epidermal Growth Factor Promotes Mesenchymal Stem Cell-Mediated Wound Healing and Hair Follicle Regeneration

4 citations , January 2017 in “PubMed”

This study found that adding epidermal growth factor to mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats compared to stem cells alone.

research Differentiation of Human Hair Follicle Stem Cells Into Endothelial Cells Induced by Vascular Endothelial and Basic Fibroblast Growth Factors

24 citations , November 2013 in “Molecular Medicine Reports”

This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.

research Nestin-Positive Hair Follicle Pluripotent Stem Cells Can Promote Regeneration of Impinged Peripheral Nerve Injury

57 citations , November 2011 in “The Journal of Dermatology”

This study found that transplanting human hair follicle pluripotent stem cells can promote the recovery of sciatic nerve function in a mouse model of nerve impingement.

The Advantages of Hair Follicle Pluripotent Stem Cells Over Embryonic Stem Cells and Induced Pluripotent Stem Cells for Regenerative Medicine

research The Advantages of Hair Follicle Pluripotent Stem Cells Over Embryonic Stem Cells and Induced Pluripotent Stem Cells for Regenerative Medicine

33 citations , October 2010 in “Journal of Dermatological Science”

This study suggests that human and mouse hair follicle stem cells may support nerve repair and provide a practical source of stem cells for neurological therapies.

research Therapeutic Potential of Stem Cells in Skin Repair and Regeneration

73 citations , August 2008 in “Chinese Journal of Traumatology”

This review outlines recent advances in using stem cells for skin repair and regeneration, suggesting potential for complete skin and appendage regeneration after severe burns, but presents no new clinical findings.

research An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution

170 citations , November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that in the absence of hair follicles, cutaneous wounds in mice showed delayed reepithelialization but eventually achieved normal wound closure after expanding the activated epidermis region.