The Advantages of Hair Follicle Pluripotent Stem Cells Over Embryonic Stem Cells and Induced Pluripotent Stem Cells for Regenerative Medicine

    October 2010 in “ Journal of Dermatological Science ”
    Yasuyuki Amoh, Kensei Katsuoka, Robert M. Hoffman
    Image of study
    TLDR Hair follicle stem cells are a practical and ethical option for nerve repair in regenerative medicine.
    The document from 2010 discusses the advantages of using hair follicle pluripotent stem cells (hfPS cells) for regenerative medicine, particularly for nerve repair. These cells, found in the hair follicle pluripotent stem cell area (hfPSCA), can differentiate into various cell types such as neurons, glia, and Schwann cells, and express the neural stem cell marker nestin. The study shows that hfPS cells can enhance nerve regeneration and functional recovery in mouse models of peripheral nerve injury, with the cells differentiating mainly into Schwann cells. The document also describes a method for isolating and culturing these cells from human hair follicles, which can form "hair spheres" and differentiate into multiple cell types. The use of hfPS cells is presented as a practical and ethically favorable alternative to embryonic stem cells and induced pluripotent stem cells, with the potential to serve as an accessible and autologous source for regenerative therapies. The number of subjects involved in the study is not mentioned.
    Discuss this study in the Community →

    Research cited in this study

    5 / 5 results

    Related Community Posts Join

    6 / 1000+ results

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Please explain this Minoxidil phenomena

      in Minoxidil  58 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community 22 yr asian male 2 year fin results

      in Progress Pictures  135 upvotes 1 year ago
      The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

    Similar Research

    5 / 1000+ results