Effects of Hair Follicle Stem Cells on Partial-Thickness Burn Wound Healing and Tensile Strength

March 2020 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”

Azar Babakhani, Malihe Nobakht, Hamidreza Pazoki‐Toroudi, Mostafa Dahmardehei, Paria Hashemi, Javad Mohajer Ansari, Parisa Ramhormozi, Abazar Yari, Fatemeh Heidari

hair follicle stem cells HFSCs collagen deposition CD31 expression vascular density tissue tensile strength

The study investigated the effects of hair follicle stem cells (HFSCs) on healing deep partial-thickness burn wounds in rats. HFSCs, isolated from rat whiskers, were injected around the wound bed, and their impact on wound healing was assessed. Results showed that HFSC-treated wounds had an accelerated closure rate, faster re-epithelialization, and increased collagen deposition compared to controls. Additionally, there was enhanced CD31 expression and vascular density, along with improved tissue tensile strength in the HFSC-treated group. The study concluded that HFSCs could significantly enhance burn wound healing and tensile strength in rats.

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