Effects of Hair Follicle Stem Cells on Partial-Thickness Burn Wound Healing and Tensile Strength

March 2020 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”

Azar Babakhani, Malihe Nobakht, Hamidreza Pazoki‐Toroudi, Mostafa Dahmardehei, Paria Hashemi, Javad Mohajer Ansari, Parisa Ramhormozi, Abazar Yari, Fatemeh Heidari

hair follicle stem cells HFSCs collagen deposition CD31 expression vascular density tissue tensile strength

TLDR Hair follicle stem cells improve burn wound healing and strength in rats.

The study investigated the effects of hair follicle stem cells (HFSCs) on healing deep partial-thickness burn wounds in rats. HFSCs were isolated from rat whiskers and injected around the wound bed. The results showed that HFSC treatment accelerated wound closure, re-epithelialization, and collagen deposition compared to control groups. Additionally, there was an increase in CD31 expression and vascular density, indicating enhanced vascularization. The tensile strength of the tissue also improved in HFSC-treated rats. Overall, the study concluded that HFSCs could significantly enhance burn wound healing and improve tissue tensile strength in rats.

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