March 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” The study investigated the effects of hair follicle stem cells (HFSCs) on healing deep partial-thickness burn wounds in rats. HFSCs, isolated from rat whiskers, were injected around the wound bed, and their impact on wound healing was assessed. Results showed that HFSC-treated wounds had an accelerated closure rate, faster re-epithelialization, and increased collagen deposition compared to controls. Additionally, there was enhanced CD31 expression and vascular density, along with improved tissue tensile strength in the HFSC-treated group. The study concluded that HFSCs could significantly enhance burn wound healing and tensile strength in rats.
22 citations
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February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
328 citations
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
January 2025 in “Biomaterials Research” The new zinc peroxide hydrogel speeds up wound healing and tissue regeneration effectively.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.