Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Promotes Skin Regeneration and Rejuvenation: From Mechanism to Therapeutics

    December 2023 in “ Cell proliferation ”
    Xixian Li, Dan Zhang, Yu Ye … Muxin Zhao
    Studysummary This review suggests that the umbilical cord-derived mesenchymal stem cell secretome presents a promising approach for skin regeneration and wound healing due to its multiple therapeutic properties, highlighting its potential over traditional treatments for conditions like chronic wounds and alopecia.
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    Research cited in this study 13

    1. Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Promotes Skin Regeneration and Rejuvenation: From Mechanism to Therapeutics Cell proliferation · 2023
    2. Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics Frontiers in cell and developmental biology · 2022
    3. Stem Cell Therapy for Burns: The Story So Far Biologics · 2021
    4. Mesenchymal Stromal Cell-Conditioned Medium for Skin Diseases: A Systematic Review Frontiers in Cell and Developmental Biology · 2021
    5. In Vitro and Clinical Evaluation of Umbilical Cord-Derived Mesenchymal Stromal Cell-Conditioned Media for Hair Regeneration Journal of Cosmetic Dermatology · 2021
    6. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021
    7. Wound Healing: Cellular Mechanisms and Pathological Outcomes Open Biology · 2020
    8. Current Advances in Stem Cell-Based Therapies for Hair Regeneration European Journal of Pharmacology · 2020
    9. Stem Cell Dynamics, Migration, and Plasticity During Wound Healing Nature Cell Biology · 2018
    10. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    11. A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice Stem Cells International · 2017
    12. Cellular and Molecular Mechanisms of Repair in Acute and Chronic Wound Healing British Journal of Dermatology · 2015
    13. Human Wharton's Jelly Stem Cells and Their Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds Journal of Cellular Biochemistry · 2013