Extracellular Vesicles from Hair Follicle-Derived Mesenchymal Stromal Cells: Isolation, Characterization, and Therapeutic Potential for Chronic Wound Healing
April 2022
in “
Stem cell research & therapy
”
extracellular vesicles hair follicle mesenchymal stromal cells chronic wound healing medium-large EVs small EVs adipose tissue-derived MSCs human dermal fibroblasts angiogenesis human umbilical vein endothelial cells oxidative stress cytotoxicity hyperglycemic environment EVs HF-MSCs chronic wounds m-lEVs sEVs AT-MSCs HDFs HUVECs
Studysummary This study found that extracellular vesicles derived from hair follicle mesenchymal stromal cells demonstrated similar potential to those from adipose tissue in promoting cell proliferation and migration, enhancing angiogenesis, and protecting cells under stress, suggesting promise for chronic wound treatment.
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