Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation
January 2022
in “
Biomedicines
”
human hair follicle-derived mesenchymal stromal cells HF-MSCs lower dermal sheath immunomodulation neural marker expression mesenchymal stem cell criteria chondrogenic differentiation osteogenic differentiation adipogenic differentiation pro-inflammatory stimuli IDO MHC-II expression immunoevasiveness PBMC proliferation cytotoxic T cells B cells regulatory T cells adipose tissue-derived MSCs AT-MSCs M2 macrophage polarization hair follicle-derived MSCs stem cell criteria
Studysummary In this study, hair follicle-derived mesenchymal stromal cells showed potential for immunomodulation, with equivalent or superior responses compared to those from adipose tissue, suggesting a promising alternative cell source.
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