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Glossary Adipogenic Differentiation

process where precursor cells become mature fat cells

Adipogenic differentiation, also known as adipocyte differentiation, is the process by which preadipocytes (precursor cells) develop into mature adipocytes (fat cells). This process involves a series of genetic and biochemical changes that enable the cells to store fat and perform functions related to energy storage and metabolism. Understanding adipogenic differentiation is crucial for research into obesity, metabolic disorders, and related conditions.

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research Cultured Cells from the Adult Human Hair Follicle Dermis can be Directed Toward Adipogenic and Osteogenic Differentiation

38 citations , April 2005 in “Journal of Investigative Dermatology”

Human hair follicle cells can become fat and bone cells, useful for therapy.

research Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells

24 citations , July 2015 in “International Journal of Molecular Sciences”

In this study, fluoxetine was found to decrease proliferation and adipogenic differentiation of human adipose-derived stem cells, suggesting it may reduce fat accumulation by increasing autophagy-related gene expression.

Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor

research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor

11 citations , May 2015 in “Stem Cells Translational Medicine”

This study found that megestrol acetate increases the proliferation, migration, and adipogenic differentiation of adipose-derived stem cells through glucocorticoid receptor phosphorylation.

research Comparative characterization and osteogenic / adipogenic differentiation of mesenchymal stem cells derived from male rat hair follicles and bone marrow

6 citations , August 2020 in “Cell regeneration”

This study found that hair follicle mesenchymal stem cells are similar to bone marrow stem cells in most characteristics, but differ in their adipogenic and osteogenic differentiation capabilities, suggesting they may be a suitable source for adipogenesis research.

research Mealworm-Derived Protein Hydrolysates Enhance Adipogenic Differentiation via Mitotic Clonal Expansion in 3T3-L1 Cells

January 2025 in “Foods”

This study found that protein hydrolysates from mealworms, especially those derived using flavourzyme, significantly enhance adipogenic differentiation in 3T3-L1 preadipocytes, suggesting their potential as sustainable ingredients for glycemic control, skin health, and tissue regeneration products.

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