Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration

    April 2015 in “ Stem Cells ”
    Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Kunihiro Tsuchida … Naohiro Hashimoto
    Studysummary This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
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