Treg–Tissue Cell Interactions in Repair and Regeneration
TLDR Treg cells help repair and regenerate tissues by interacting with local cells.
The review "Treg–tissue cell interactions in repair and regeneration" examines the role of regulatory T (Treg) cells in tissue repair and regeneration, highlighting their interactions with various tissue cells such as epithelial, mesenchymal, and endothelial cells. Treg cells produce mediators like amphiregulin (Areg) and cytokines (e.g., IL-10, TGF-β) that aid in processes like wound healing, hair follicle regeneration, and recovery from lung, muscle, and brain injuries. The review underscores Treg cells' dual role in immunosuppression and direct tissue repair, suggesting potential therapeutic applications for enhancing tissue repair in clinical settings. Further research is needed to understand Treg cells' functions in chronic diseases and cancer.
