Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.

This review summarizes recent findings about the multi-site differentiation of tissue regulatory T cells, emphasizing the pivotal role of epigenetic remodeling, but it reports no new clinical results.

This review discusses how regulatory T cells, known for their immunosuppressive role, also produce repair mediators critical for tissue repair and regeneration, acting on non-immune cells in tissue-specific contexts, and highlights areas for future research in tissue repair, fibrosis, and cancer.