Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures
May 2023
in “
Cytotherapy
”
extracellular vesicles hair follicle mesenchymal stromal cells adipose mesenchymal stromal cells neuroprotective effects anti-inflammatory effects dopaminergic primary cell cultures pro-inflammatory cytokines microglial cell cultures EVs HF-MSCs AT-MSCs neuroprotection anti-inflammation dopaminergic cells cytokines microglia
Studysummary This study found that medium/large extracellular vesicles derived from hair follicle and adipose tissue mesenchymal stromal cells both demonstrated significant neuroprotective and anti-inflammatory effects in cell cultures, highlighting their potential use as biopharmaceuticals for treating neurodegenerative diseases.
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