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GlossaryAdipose-Derived Stem Cells

stem cells harvested from fat tissue for regenerative purposes

Adipose-Derived Stem Cells (ADSCs) are stem cells that are harvested from fat tissue. These cells have the ability to differentiate into various cell types, including bone, cartilage, and muscle cells, making them valuable for regenerative medicine and tissue engineering. They are also being researched for their potential in treating conditions like alopecia, as they can promote hair growth and repair damaged hair follicles.

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Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

research Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

May 2023 in “Cytotherapy”

Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.

research Soy Protein/Beta-Chitin Sponge-Like Scaffolds Laden With Human Mesenchymal Stromal Cells Promote Diabetic Chronic Wound Healing

1 citations, December 2023 in “Biomaterials advances”

Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.

Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis

research Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis

5 citations, August 2020 in “Stem Cell Research & Therapy”

Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.

research Extracellular Vesicles from Hair Follicle-Derived Mesenchymal Stromal Cells: Isolation, Characterization, and Therapeutic Potential for Chronic Wound Healing

22 citations, April 2022 in “Stem cell research & therapy”

Hair follicle-derived extracellular vesicles may help heal chronic wounds as effectively as those from adipose tissue.

research Cell and Cell-Free Therapies in Osteoarthritis

10 citations, November 2021 in “Biomedicines”

Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.

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community Anyone Try Microneedling with Exosomes/AAPE?

in Microneedling 2 upvotes 2 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

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