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Glossary Anti-inflammatory

reduces inflammation and alleviates associated symptoms

An anti-inflammatory is a substance or medication that reduces inflammation, which is the body's response to injury or infection characterized by redness, swelling, pain, and heat. Common examples include nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and corticosteroids, which are often used to treat conditions such as arthritis, allergies, and autoimmune diseases.

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Research

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research Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract

9 citations , June 2022 in “Plants”

This study found that shallot extract may promote hair growth in androgenetic alopecia by reducing inflammation and modulating gene expression related to key hair growth pathways.

research Palmitoylethanolamide-Incorporated Elastic Nano-Liposomes for Enhanced Transdermal Delivery and Anti-Inflammation

8 citations , June 2024 in “Pharmaceutics”

This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.

research Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances

7 citations , January 2022 in “Plants”

This study found that extracts from the rice variety Bue Bang 3 CMU, particularly the husk and bran, demonstrated antioxidant, anti-inflammatory, and anti-androgenic properties, suggesting potential use in treating androgenetic alopecia.

research Wound Healing Effect of Supercritical Carbon Dioxide Datura metel L. Leaves Extracts: An In Vitro Study of Anti-Inflammation, Cell Migration, MMP-2 Inhibition, and the Modulation of the Sonic Hedgehog Pathway in Human Fibroblasts

6 citations , July 2023 in “Plants”

This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.

research Local anti-inflammatory effect and immunomodulatory activity of chitosan-based dressing in skin wound healing: a systematic review

4 citations , November 2022 in “Journal of clinical and translational research”

This systematic review found that chitosan-based wound therapy may accelerate wound healing by reducing inflammation and modulating immune response, but notes limited clinical trials to date.

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Community Join

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community Anti inflammatories as an adjunct treatment

1 upvotes 9 months ago

Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.

community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 8 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community Inflammation's surprising role in shrinking hair follicles and AGA

in Technology 66 upvotes 4 months ago

Inflammation plays a significant role in hair follicle miniaturization and androgenetic alopecia, with treatments like ketoconazole shampoo, minoxidil, and finasteride being used to address it. Users discuss the benefits of anti-inflammatory treatments and peptides like KPV, alongside traditional hair loss treatments, to improve scalp health and hair quality.

community Severe diffuse thinning after scalp inflammation – should I keep fighting or just accept it?

in Finasteride/Dutasteride 4 upvotes 11 months ago

A 23-year-old experiencing severe diffuse thinning after scalp inflammation is considering finasteride as a last resort after stopping minoxidil and using anti-inflammatory medication. Users suggest that inflammation causes temporary shedding and recommend consulting a dermatologist, with some advocating for finasteride as a reliable treatment option.

community Rosemary Oil for inflammatory hairloss? Recommendations?

5 upvotes 1 year ago

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

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Learn

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learn Cetirizine

Antihistamine allergy medicine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is a few small trials in pattern hair loss (none in inflammatory scalp disease), so scalp use is off-label and experimental.

learn Centella

Hormone-related scalp sensitivity: is there evidence for a centella mask? Centella asiatica has anti-inflammatory and wound-healing effects in animal and cell studies, but no published research has tested a centella scalp mask on the human scalp, in hormonal contexts or otherwise, and no community reports were found of one being used this way.

learn Hair Transplant

Do I need to take medication after a hair transplant? Clinics often prescribe short courses of antibiotics and anti-inflammatory medicines; many also suggest minoxidil or finasteride to protect non-transplanted hair, a choice to make with your prescriber.
What medications should I avoid before hair transplant surgery? Clinics often ask patients to pause blood thinners, anti-inflammatories and some supplements before surgery. Only stop a prescribed medicine with your prescribing doctor's approval.

learn Bicalutamide

Nonsteroidal anti-androgen, originally a prostate cancer drug

learn procapil

Getting bald patches? What is and isn't known about Procapil and immune-related hair loss Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

learn Azelaic Acid

Acid used in acne and rosacea creams

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Lavender

Plant essential oil used in scalp products

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Clinics

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Experts

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Dermatologist
Andi Iryanti, M. Biomed
Indonesia

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Andi Iryanti, M. Biomed