Preclinical Efficacy and Safety Evaluation of a Topical Mesenchymal Stem Cell Derived Conditioned Media Gel for Oral Mucositis Management

    February 2026 in “ Scientific Reports ”
    Caroline Mathen, Wilfrid Dsouza, Deepali Sharma … Jyoti Kode
    Studysummary This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.
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    3. In Vitro and Clinical Evaluation of Umbilical Cord-Derived Mesenchymal Stromal Cell-Conditioned Media for Hair Regeneration Journal of Cosmetic Dermatology · 2021
    4. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences · 2021